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QUESTION OF THE MONTH & VISUAL PEARL
January 2023 QUESTION OF THE MONTH
A 17-year-old girl presents to your chronic pain clinic with neuropathic pain of her right leg secondary to osteosarcoma of the right femur. She has severe persistent neuropathic pain despite treatment with pregabalin, duloxetine, physiotherapy, and psychological treatments. The teen and her parents are interested in exploring cannabinoids for treatment of her pain and want to discuss this further with you. Which one of the following statements is incorrect?
A. Recent systematic review on cannabinoids as medical treatment in children and adolescents showed insufficient evidence for its use in chronic pain conditions such as spasticity and neuropathic pain.
B. There is evidence from recreational cannabis users suggesting the chronic use of cannabis may have adverse effects on the developing brain.
C. Nabilone is an orally administered synthetic cannabinoid and analogue of cannabidiol (CBD).
D. In a small cohort study on the use of nabilone in children with severe non-cancer pain, the most common reported side effects were sedation and cognitive slowing.
December 2022 VISUAL PEARL