Society for Pediatric Pain Medicine

January 2023 QUESTION OF THE MONTH

A 17-year-old girl presents to your chronic pain clinic with neuropathic pain of her right leg secondary to osteosarcoma of the right femur. She has severe persistent neuropathic pain despite treatment with pregabalin, duloxetine, physiotherapy, and psychological treatments. The teen and her parents are interested in exploring cannabinoids for treatment of her pain and want to discuss this further with you. Which one of the following statements is incorrect?

A. Recent systematic review on cannabinoids as medical treatment in children and adolescents showed insufficient evidence for its use in chronic pain conditions such as spasticity and neuropathic pain.

B. There is evidence from recreational cannabis users suggesting the chronic use of cannabis may have adverse effects on the developing brain.

C. Nabilone is an orally administered synthetic cannabinoid and analogue of cannabidiol (CBD).

D. In a small cohort study on the use of nabilone in children with severe non-cancer pain, the most common reported side effects were sedation and cognitive slowing.

Answer the Question

December 2022 VISUAL PEARL

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SPPM is NOW on YouTube!

SPPM has launched an official YouTube channel where our latest videos including our popular Visual Pearl series are available for easy access and education. Subscribe to our channel here: www.youtube.com/@PedsPainMed

Improving Preclinical Development of Novel Interventions to Treat Pain: Insanity is Doing the Same Thing Over and Over and Expecting Different Results

New Study on Quadratus Lumborum Catheters for Perioperative Analgesia

A case series has been published looking at a preliminary group of pediatric patients who received quadratus lumborum catheters as proxy for epidurals. All catheters functioned successfully and were in place for a median of 79.3 h. Other than early inadvertent removal of two catheters, no adverse effects were noted. Read the paper here: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9635806/pdf/jocmr-14-425.pdf […]

Synthetic Cannabinoid for the Treatment of Severe Chronic Noncancer Pain in Children and Adolescents

A new study published in the Canadian Journal of Pain has shared the experience of one pediatric chronic pain program and their positive experience with the of use of nabilone for pediatric non-cancer pain. Study can be found here: https://www.tandfonline.com/doi/epdf/10.1080/24740527.2022.2132138?needAccess=true&role=button

Prescribing Opioids in Pain – A Perspective of the New CDC Guidelines

In response to the CDC’s Clinical Practice Guideline for Prescribing Opioids for Pain, perspective letter has been published in The New England Journal of Medicine. The paper provides a summary of the guidelines and also highlights changes that have been made since the last guideline that was published in 2016. Follow the link to […]

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QUESTION OF THE MONTH & VISUAL PEARL

SPPM is NOW on YouTube!

Improving Preclinical Development of Novel Interventions to Treat Pain: Insanity is Doing the Same Thing Over and Over and Expecting Different Results

New Study on Quadratus Lumborum Catheters for Perioperative Analgesia

Synthetic Cannabinoid for the Treatment of Severe Chronic Noncancer Pain in Children and Adolescents

Prescribing Opioids in Pain – A Perspective of the New CDC Guidelines

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