Zero Patient-controlled Analgesia is an Achievable Target for Postoperative Rapid Recovery Management of Adolescent Idiopathic Scoliosis Patients

2021 Poster Winners
In order to amplify and learn from award winning research by our membership, we will be sharing posters from the 2021 SPPM meeting. This month, we have chosen a poster by Packiasabathy et al. on multi-dose methadone use in children undergoing spine fusions.
A novel perioperative multi-dose methadone-based multi-modal analgesic strategy achieves safe blood methadone levels, enabling opioid sparing sustained analgesia with no respiratory depression in children undergoing spine fusions
Packiasabapathy S, Aruldhas B, Fitzgerald R, Quinney S, Sadhasivam S
Indiana University School of Medicine, Indianapolis, Indiana, United states
CLICK HERE to view the Poster.
Guidelines Emphasize Need for Multimodal, Individualized Care for Surgery Patients
A recently published article summarizes guidelines outlining seven guiding principles for acute perioperative pain management to help institutions better care for patients having surgery. Despite being adult focused, these guidelines are relevant to pediatric care as well.
CLICK HERE to read the article.
Question of the Month – October 2021
There is a strong evidence base for the association between sleep and pain. Researchers have grappled with the direction of causality—can sleep disturbance increase pain? Prospective studies have found evidence for sleep disturbance preceding pain exacerbations in individuals with chronic pain. Studies suggest that as little as _____ of sleep disturbance can result in increased pain.
Sleep is a highly complex process that is essential for recuperation, memory, emotional modulation, performance and learning.1 Disturbances in sleep have been shown to impact all areas of functioning as well as acute and chronic pain in children.2 The directionality between sleep and pain, where poor sleep results in increased pain or increased pain results in poor sleep, have been highly debated. In adult populations, more recent evidence has showed a stronger effect of poor sleep resulting in worsening pain as opposed to the bidirectional relationship that was previously thought.1 A single night of sleep deprivation in patients with arthritis resulted in increased self-reported pain.3 Further, experimental studies in healthy volunteers showed that two nights of poor sleep resulted in spontaneous bodily pain after partial sleep deprivation.3
The pediatric literature is less clear. In the acute pain setting, evidence seems to indicate that poor sleep was associated with greater next day pain.4 In youth with sickle cell disease, pain and sleep seemed to be bidirectional.5 Comorbidities and socioeconomic factors also affect sleep in children.6,7 Although further studies are needed to establish the sleep-pain relationship, poor sleep in children with pain should be addressed and improved.
References:
1. Babiloni AH, De Koninck BP, Beetz G, De Beaumont L, Martel MO, Lavigne GJ. Sleep and pain: recent insights, mechanisms, and future directions in the investigation of this relationship. Journal of Neural Transmission. 2020;127:647-660.
2. Valrie CR, Bromberg MG, Palermo T, Schanberg LE. A Systematic Review of Sleep in Pediatric Pain Populations. J Dev Behav Pediatr. 2013;34(2):120-8.
3. Finan, PH, Goodin BR, Smith MT. The association of sleep and pain: an update and a path forward. J Pain. 2013;14(12): 1539-1552.
4. Rabbitts JA, Zhou C, Narayanan A, Palermo TM. Longitudinal and Temporal Associations Between Daily Pain and Sleep Patterns After major Pediatric Surgery. J Pain. 2017;18(6):656-663.
5. Fisher K, Laikin AM, Howard Sharp KM, Criddle CA, Palermo TM, Karlson CW. Temporal relationship between daily pain and actigraphy sleep patterns in pediatric sickle cell disease. J Behav Med. 2018;41(3):416-422.
6. Allen JM, Graef DM, Ehrentraut JH, Tynes BL, Crabtree VM. Sleep and Pain in Pediatric Illness: A Conceptual Review. CNS Neurosci Ther. 2016;22(11):880-893.
7. Evans S, Taub R, Tsao JCI, Meldrum M, Zeltzer LK. Sociodemographic factors in a pediatric chronic pain clinic: The roles of age, sex and minority status in pain and health characteristics. J Pain Manag. 2010;3(3):273-281.
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