Ex 34-week infant who was born to a mother with a history of severe Osteogenesis Imperfecta (OI) and chronic pain on chronic opioid therapy. Throughout her pregnancy, the mother was on methadone 15mg TID, and PRN hydrocodone/acetaminophen (dose weaned from 100 mg/day earlier in pregnancy to 30mg/day in an attempt to limit fetal exposure). The inpatient pain service was consulted for evaluation and treatment of NAS and ongoing pain issues.

Which of the following statements is true?