A new systematic review published in Anesthesia & Analgesia by Dr. Sapna Kudchadkar’s group at Johns Hopkin’s Children’s Centre examines the effects of intraoperative methadone for postoperative pain control. Although the studies had methodological issues, it was noted that there was decreased consumption of opioids in the first 24 hours postoperatively compared to patients receiving other shorter-acting opioids or pain management strategies. 

Read the full paper HERE