US Pain Foundation publishes Pediatric Pain Report
In early 2021, the Pediatric Pain Warrior program at U.S. Pain Foundation surveyed 125 families with one or more children living in pain. The results paint a portrait of families and children affected by chronic pain whose needs are not being met.
Read the full report HERE.
Question of the Month – August 2021
Membrane stabilizers are commonly used to treat both acute and chronic pain in children and adolescents. Which of the following is the MOST likely mechanism of gabapentin?
Although early proposed mechanisms of gabapentin were interaction by activation of the GABAB receptors containing the GABAB1a and GABAB2 subunits, thereby enhancing NMDA current or inhibiting AMPA-receptor-mediated transmission to the spinal cord, more recent studies have instead favored selective inhibition at the α2δ-1 subunit of spinal N-type Ca (2+) channels.
References:
1. Chen J, Li L, Chen SR, et al. The α2δ-1-NMDA Receptor Complex Is Critically Involved in Neuropathic Pain Development and Gabapentin Therapeutic Actions. Cell Rep. 2018;22(9):2307-2321. doi:10.1016/j.celrep.2018.02.021
2. Cheng JK, Chiou LC. Mechanisms of the antinociceptive action of gabapentin. J Pharmacol Sci. 2006;100(5):471-86. doi: 10.1254/jphs.cr0050020. Epub 2006 Feb 11. PMID: 16474201.
3. Li G, Li P. (2020, Summer) The use of membrane stabilizers in acute and chronic pain. SPPM Newsletter. Retrieved from https://pedspainmedicine.org/wp- content/uploads/newsletters/2020/summer/nonopioid/Membrane%20Stabilizers%20.html
4. Sills GJ, Rogawski MA. Mechanisms of action of currently used antiseizure drugs. Neuropharmacology. 2020 May 15;168:107966. doi: 10.1016/j.neuropharm.2020.107966. Epub 2020 Jan 14. PMID: 32120063.
1st Pain360 Congress
1st Pain360 Congress
1 – 3 December 2021
Austria, Vienna
pain-360.org
Pain360 is an innovative, multidisciplinary medical event, covering contemporary, holistic techniques and approaches to pain management and treatment, taught by experienced experts at the top of their field.
The Congress will include practical workshops, hands-on training and scientific sessions discussing the lastest innovations in pain science, providing essential knowledge and experience to professionals dealing with any kind of pain, enabling them to acquire the skills in pain management needed to benefit the lives of their patients.
Help us bridge the gap between pain disciplines and revolutionize the pain field by joining the 1st Pain360 Congress in Vienna, Austria between 1-3 December 2021 for 3 exciting days of insightful education, hands-on trainings, shared knowledge, collaboration and inspiration.
Learn more at pain-360.org .
Pediatric Patients Need Appropriate Pain Management After Surgery
Drs. Rita Agarwal, Vidya Chidambaram and Stephen Hays were featured in an article and podcast on the well known KevinMD platform regarding JAMA Surgery’s published guidelines on opioid use for acute pain management. CLICK HERE to review these guidelines and letter to the editor.
CLICK HERE for the podcast.
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